Regulating air treatment in clean rooms: a strategic challenge for performance

Ensuring air quality in a cleanroom is not just a technical issue: it is a strategic challenge for process reliability, critical environment safety and regulatory compliance.

In his article published in June 2025 in Salle Propre magazine, Maxime Guyonnet reminds us how air treatment control is an essential link in the success of a cleanroom project.

Why is air control so crucial?

In a cleanroom, everything depends on balance:

• Air flow rates and pressure gradients to maintain the integrity of the environment,
• Temperature and humidity to ensure stable conditions,
• Safety and comfort to protect both products and operators.

The slightest fluctuation can compromise the quality, compliance and overall performance of the facility.

An integrated approach from the design stage

Maxime Guyonnet emphasises the need to integrate control from the design phase. This choice makes it possible to anticipate regulatory constraints and ensure precise control of environmental conditions.

Failure to do so risks the need to add costly, less efficient and more difficult to control solutions at a later stage.

Unavoidable regulatory requirements

Standards such as ISO 14644, BPF (ANSM) and GMP (FDA) impose strict criteria for air renewal and quality.

Air treatment regulation is therefore essential, not only to ensure regulatory compliance, but also to preserve the reputation and competitiveness of industrial players (pharmaceuticals, microelectronics, healthcare, etc.).

A complex but strategic process

Clean room regulation combines:

• technical challenges (advanced measurement and control systems),
• regulatory issues (strict compliance with standards),
• energy requirements (efficiency and cost optimisation).

It is precisely this complexity that makes it a strategic skill for any controlled environment project.

Conclusion

Air treatment control in clean rooms is not an option, but a prerequisite for success. As Maxime Guyonnet points out, it must be thought out in advance, integrated into design choices, and rigorously managed to combine compliance, performance and sustainability.

In a context where quality and safety brook no compromise, investing in controlled air regulation means investing in the future of your projects in critical environments.

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